Indoor air generally contains levels of benzene higher than those in outdoor air. Benzene is known to be responsible for a number of health disorders, and is linked with various types of leukemia amongst other illnesses. Smith MT(1). Can harm the nervous system. Working with benzene may affect your health. Anything that touches the contaminated clothing should also be placed in the bag. It is highly mobile in soils and Other products with benzene Within the chemical industry, benzene uses are mainly to produce other chemicals. That means 1 part benzene for every 1 million parts of air over the course of an 8-hour day. The Environmental Protection Agency (EPA) identifies the most serious hazardous waste sites in the nation. It is harmful to the eyes, skin, airway, nervous system, and lungs. Eye contact. Effects include fatigue, headache, dizziness, nausea, loss of appetite, loss of weight, and weakness. Benzene exposure can result in a number of neurological symptoms, and these include dizziness, drowsiness, headaches, and loss of consciousness. CDC twenty four seven. It has a sweet odor and is highly flammable. Benzene is a colorless liquid with a sweet odor. If you wear contacts, remove them after washing your hands and put them with the contaminated clothing. Short-term Background Ethylbenzene belongs to a group of chemicals called "BTEX compounds", which also includes benzene, toluene and xylene. What is benzene? If you think your water supply may have benzene in it, drink bottled water until you are sure your water supply is safe. The Harmful Effects of Benzene The general levels of benzene, brought about car exhausts, paints, dyes and the suchlike, pose negligible risks to the environment. Benzene is also used to make some types of lubricants, rubbers, dyes, detergents, drugs, and pesticides. Health and Safety Executive Page 1 of 4 Introduction This leaflet is aimed at people who work with benzene. Inhalation: Can irritate the nose and throat. Objectives: To study environmental exposure to benzene as well as hematological effects of benzene exposure in taxi drivers. It decreases red blood cells and damages bone marrow. Benzene is widely used in the United States. Health Details: Those working with Benzene products are classed as a high risk group, and this is because these people are at increased risk of dangerous exposure levels of Benzene, which can result in …Aplastic Anemia. If you wear eyeglasses, wash them with soap and water. To receive email updates about this page, enter your email address: Centers for Disease Control and Prevention. %PDF-1.5 %���� Benzene - Benzene Health Effects. %%EOF For example, small amounts of benzene, which are not harmful, can be found in fruit, fish or vegetables, according to the U.S. National Library of Medicine. 369 0 obj <>stream If you are helping other people remove their clothing, try to avoid touching any contaminated areas, and remove the clothing as quickly as possible. The major effect of benzene from long-term exposure is on the blood. Benzene is a ubiquitous chemical in our environment that causes acute leukemia and probably other hematological cancers. Benzene health effects killing your immune system? Long-term exposure can cause problems in blood production and affect the bone marrow. Long-term exposure to high levels of benzene in the air can cause leukemia, cancer of the blood-forming organs. Chemicals Listed Effective December 26, 1997 as Known to the State to Cause Reproductive Toxicity: Benzene; December 9, 1997 Meeting of the Developmental and Reproductive Toxicant (DART) Identification Committee; Notice of Proposed Rulemaking, Amendments to Sections 12705 (10 chemicals) and 12805 (arsenic) Other products with benzene. First, if the benzene was released into the air, get fresh air by leaving the area where the benzene was released. Also, it can damage the immune system by changing blood levels of antibodies and causing the loss of white blood cells. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. Benzene is a colourless, volatile liquid with a characteristic sweet odour. Its vapor is heavier than air and may sink into low-lying areas. Smith MT. Sudden exposure to high levels of benzene requires a hospital treatment. Objective: To assess health risks associated with inhalation exposure to formaldehyde and benzene mainly emitted from building and decoration materials in newly remodeled indoor spaces in Beijing. Dial 911 and explain what has happened. Benzene released into surface water evaporates in a few hours. 2018 Mar;48(3):217-251. doi: 10.1080/10408444.2017.1401581. Repeated or prolonged skin contact with liquid benzene can remove the natural oils from the … h޴V[o�8�O�#hDm�i�D�\VC� Cancer: Because benzene is known to cause genetic damage, it’s a well-established carcinogen. A literature review of the impact on human health of exposure to benzene was conducted. Ingested in food or drinking water, benzene is a known carcinogen, causing leukemia. 339 0 obj <> endobj You can put your eyeglasses back on after you wash them. Natural sources of benzene include volcanoes and forest fires. Disposing of your clothing in this way will help protect you and other people from any chemicals that might be on your clothes. Benzene is also a natural part of crude oil, gasoline, and cigarette smoke. Benzene health effects. The short term exposure limit is 5 ppm for any 15-minute period. The level of exposure depends upon the dose, duration, and work being done h�b```b``Vd`�'@ (�K>�7^Ʊ��9úw���:���]:�޹�6�7+�З��Y�;::X@d2��^��р0�����4�Fa`4bf8�]$(#��ː�����A�A�,�9�P&��:Q��o@(���BL��@���A�>X����``�q�(c�` �C3y Benzene leaks from underground storage tanks or from hazardous waste sites containing benzene can contaminate well water. Benzene (C6H6) is a highly flammable, colorless liquid that evaporates quickly into the air. Disaster Medicine & Public Health Prep. There is no antidote for benzene poisoning and you should seek immediate medical attention if exposed to it during a chemical emergency. For example, it can cause bone marrow not to produce enough red blood cells, which can lead to anemia. The objective of this retrospective study was to evaluate the health consequences of benzene exposure in children following a flaring incident at … Shanghai Health Study (2001-2009): What was learned about benzene health effects? 2016 Read More Because of its propensity to react with other elements in the air, it is most often quickly diffused within a few days of exposure and therefore it is virtually harmless. Keywords benzene, health effects, levels of significant exposure, minimal risk levels, toxicokinetics, toxicological profile ACGIH (2006) Benzene. Benzene is an important organic chemical compound with the chemical formula C 6 H 6. Everyone is exposed to a small amount of benzene every day, most Avoid touching contaminated areas of the clothing. Quickly take off clothing that may have benzene on it. Health Effects of the Chemicals Find commonly asked questions and answers about chemicals found at Camp Lejeune and their human health effects. Long-term (a year or more) exposure to benzene can produce changes in the blood. Exposure to benzene can lead to multiple alterations that contribute to the leukemogenic process, indicating a multimodal mechanism of action. It ranks in the top 20 chemicals for production volume. Benzene 2009--Health effects and mechanisms of bone marrow toxicity: implications for t-AML and the mode of action framework. 2010;31(1):133–48. Inhalation: Can irritate the nose and throat. Special emphasis in this report is given to the health effects reported in … Bird MG(1), Greim H, Kaden DA, Rice JM, Snyder R. Author information: (1)ExxonMobil Benzene can cause blood cancers like leukemia. A disruption of normal blood production can result in conditions such as anaemia or excessive bleeding. These sites are then placed on the National Priorities List (NPL) and are targeted for long-term federal clean-up activities. Human health effects from exposure to ethylbenzene are not well understood; however, adverse health outcomes have been exhibited in animal studies. Centers for Disease Control and Prevention (CDC), National Institute for Occupational Safety and Health (NIOSH). Benzene Exposure: What Are the Long-Term Health Effects? Any clothing that has to be pulled over the head should be cut off the body instead of pulled over the head. Headaches, sleep disturbances, irritability, confusion, memory loss and nerve damage in the extremities (arms and legs) may occur with persistent exposure to benzene vapors. Benzene dissolves only slightly in water and will float on top of water. Adverse health effects due to long-term benzene exposure are non-specific. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. Can harm the nervous system. The Department of Health and Human Services (DHHS) has determined that benzene causes cancer in humans. Benzene Health Effects: Acute and Chronic - Clean Water . If you can’t avoid touching contaminated areas, or you aren’t sure where the contaminated areas are, wear rubber gloves or put the clothing in the bag using tongs, tool handles, sticks, or similar objects. Benzene is a chemical that is a colorless or light yellow liquid at room temperature. Human exposure to benzene has been associated with a range of acute and long-term adverse health effects and diseases, including cancer and haematological effects. This puts people at risk for aplastic anemia and excessive The benzene in indoor air comes from products that contain benzene such as glues, paints, furniture wax, and detergents. Short-term exposure to highly concentrated benzene vapors may cause decreased consciousness, stupor, … Within the chemical industry, benzene uses are mainly to produce other chemicals. Benzene is widely used in the United States; it ranks in the top 20 chemicals for production volume. Benzene is an excellent ligand in the organometallic chemistry of low-valent metals. It has again been the subject of much criticism by industry consultants to which the NCI-CAPM investigators have responded . However breathing very high levels of benzene, or eating or drinking foods contaminated with high levels of benzene, can cause serious health effects or … If someone has swallowed benzene, do not try to make them vomit or give them fluids to drink. People who inhale benzene for long periods of time (months or years) at high enough levels may experience harmful effects in the tissues that form blood cells, especially the bone marrow. No specific antidote exists for benzene poisoning. Eye contact. Evidence for an association with childhood leukemia is growing. In the short term, benzene can irritate the respiratory tract as well as the eyes, skin, and mucus membranes. The air around hazardous waste sites or gas stations can contain higher levels of benzene than in other areas. Crit Rev Toxicol. Pollution from Canadian refineries an ‘embarrassment’ compared to U.S. A refinery in Sarnia, Ont., and a refinery in Detroit. If the benzene release was outside, move away from the area where the benzene was released. Benzene is considered a toxic and carcinogenic (cancer-causing) chemical that causes both acute and chronic health effects. Working with benzene may affect your health. Skin contact. Adverse effects of the chemical substance depend on the level of exposure, and the duration one is exposed to the harmful chemical. Background: Exposure to benzene has been associated with adverse health effects, including haematopoietic disorders. Health and Safety Executive Page 1 of 4 Introduction. What are the potential health effects of benzene? We do not know what human health effects might occur after long-term exposure to food and water contaminated with benzene. By WhatGo - 6:21 AM. However, benzene can also have long lasting health effects stemming from long-term exposure (a year or more) such as : A reduction in the number of red blood cells, causing anemia. Workers may be harmed from exposure to benzene. h�bbd``b`z"l�c�`M�d��1 !X $���w+�`��! This leaflet is aimed at people who work with benzene. Article PubMed PubMed Central Google Scholar 23. After you have washed yourself, place your clothing inside a plastic bag. Breathing in high doses of benzene can affect the nervous system, which can lead to drowsiness, dizziness, headaches, tremors, confusion, and/or unconsciousness. It can also cause excessive bleeding and can affect the immune system, increasing the chance for infection. It is a volatile organic compound that is used commonly in the manufacture of many products including plastics, rubbers, dyes, and synthetic fibers, and is also found in gasoline and cigarette smoke. You can also find out more about additional health effects, including the various cancers that can be caused by exposure to benzene. However, because of benzenes health effects and many restrictions, it is not used as a solvent in the same extent as it was before. Author information: (1)Superfund Research Program, Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, California 94720-7356, USA. ���xH�K� J; Ig�)�l���� �cF,�!�㰺�x��i����5 ��e���r��6�&��Z�3τ�M��!-Z`�u��-l�>*�Q,}�LoÃ�LE�|�eR�]�:�N��"���"�Y>K����_c`��Ȍ#4�A��12��N�bƕ�a})u����D?�\���o�>]���DD*�Kş��곡���:,DD,ۃ��o��F�)P=�@���or�w�&���N���v�L]��g9Y�P If the benzene release was indoors, get out of the building. In animals, exposure to food or water contaminated with benzene can damage the blood and the immune system and can cause cancer. Benzene works by causing cells not to work correctly. Direct exposure of the eyes, skin, or lungs to benzene can cause tissue injury and irritation. Skin contact. Effects on Human Health . Seal the bag, and then seal that bag inside another plastic bag. Adverse health effects due to long-term benzene exposure are non-specific. The most important thing is for victims to seek medical treatment as soon as possible. Detrimental Health Effects of Benzene Exposure in Adults Exposure to benzene is associated with serious adverse health effects resulting in chronic organ toxicity.. The long-term effects of chronic exposure to benzene can be seriously damaging and cause life-altering health conditions such as: 8 Cancer: Because benzene is known to cause genetic damage, it’s a well-established carcinogen. Benzene and leukemia focuses on the carcinogenic effects of benzene, detailing the different types of leukemia that can result from exposure to this chemical, as well as discussing past studies that illustrated a link between benzene exposure and leukemia. 0 Authors Sherilyn A , … 353 0 obj <>/Filter/FlateDecode/ID[<7BF3F4D77582D34DA133325198E9E56B>]/Index[339 31]/Info 338 0 R/Length 77/Prev 103194/Root 340 0 R/Size 370/Type/XRef/W[1 2 1]>>stream photo src: www.federalregister.gov. Do not put the contacts back in your eyes (even if they are not disposable contacts). Ingestion of large amounts of benzene may result in vomiting, dizziness, and convulsions in humans. It is described as an ‘aromatic’ hydrocarbon; each molecule of benzene is composed of a ring of 6 carbon atoms (each connected to a hydrogen atom). Benzene has been shown to cause cancer in both sexes of multiple species of laboratory animals exposed via various routes. Advances in understanding benzene health effects and susceptibility. endstream endobj 340 0 obj <>/Metadata 22 0 R/OCProperties<>/OCGs[354 0 R]>>/PageLabels 335 0 R/PageLayout/OneColumn/Pages 337 0 R/PieceInfo<>>>/StructTreeRoot 59 0 R/Type/Catalog>> endobj 341 0 obj <>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageC/ImageI]/Properties<>/XObject<>>>/Rotate 0/StructParents 0/Tabs/S/Type/Page>> endobj 342 0 obj <>stream Benzene is a colorless chemical found naturally in the air and earth deposits like oil. Health effects which contains information on the health effects of benzene including the unit cancer risk for inhalation exposure. Benzene: health effects, incident management, and toxicology Information on benzene, for use in responding to chemical incidents. Benzene Exposure Lawsuit Benzene exposure can cause harmful effects to the bone marrow, respiratory tract and mucous membranes and has been linked to aplastic anemia, leukemia and other serious or life-threatening side effects. Microbes in soil can break down benzene. It decreases red blood cells and damages bone marrow. Moving to an area with fresh air is a good way to reduce the possibility of death from exposure to benzene in the air. Effects include fatigue, headache, dizziness, nausea, loss of appetite, loss of weight, and weakness. Health Effects of Benzene Acute exposure to benzene produces toxic effects on the central nervous system; however, in order to evaluate the chronic effects, consideration must be given to the myelotoxic and possible chromosome damaging and leukemogenic effects of benzene. A severe exposure can cause unconsciousness. Advances in understanding benzene health effects and susceptibility. MI., have much in common. Ingestion of benzene can cause vomiting, tachycardia, ataxia, somnolence, loss of consciousness, delirium, chemical pneumonitis with initial excitatory symptoms followed … It is not known whether benzene exposure affects the developing fetus in pregnant women or fertility in men. People working in industries that make or use benzene may be exposed to the highest levels of it. Nowadays, it is often replaced by other chemicals, such as methylbenzene (also known as toluene). Adverse effects of the chemical substance depend on the level of exposure, and the duration one is exposed to the harmful chemical. Human exposure to benzene has been associated with a range of acute and long-term adverse health effects and diseases, including cancer and haematological effects. Benzene is formed from both natural processes and human activities. �5���A��0��0:���B����0. ----- HEALTH EFFECTS OF BENZENE: A REVIEW SUMMARY Acute exposure to benzene produces toxic effects on the central nervous system; however, in order to evaluate the chronic effects, con The time required for expression of chronic benzene toxicity indicates a vast difference in individual sensitivity. Public Health Fact Sheet page 1 Benzene: Health effects Benzene is released into the air from many sources including car exhaust, petrol, smoke from tobacco and bushfires and from industry. The vast proportion of benzene is currently obtained from crude oil by processes known as ‘cracking’, ‘reforming’ or ‘disproportionation’. This study considerably expanded the health effects associated with benzene beyond AML and suggested benzene produced effects at levels lower than previously thought. Uses Benzene is used as a constituent in motor fuels; as a … This public health statement tells you about benzene and the effects of exposure to it. ATSDR’s Camp Lejeune studies of people exposed occupationally or environmentally to TCE, PCE, vinyl chloride and benzene. For more information on evacuation during a chemical emergency, see “. What are the Potential Health Effects of Benzene? Some industries use benzene to make other chemicals that are used to make plastics, resins, and nylon and synthetic fibers. However, benzene can also have long lasting health effects … Benzene causes cancer in animals including humans. It evaporates into the air very quickly and dissolves slightly in water. Performing CPR on someone who has swallowed benzene may cause them to vomit. But they can only detect a recent exposure and cannot predict future health effects. Special emphasis in this report is given to the health effects reported in excess of national norms by participants in the Benzene Subregistry of the National Exposure Registry— people having documented exposure to benzene through the use of benzene-contaminated water for domestic purposes. Important examples include the sandwich and half-sandwich complexes, respectively, Cr(C 6 H 6) 2 and [RuCl 2 (C 6 H 6)] 2. Also, if you are sure the person has swallowed benzene, do not attempt CPR. What are the potential health effects of benzene? What are the health effects of Benzene? Human exposure to benzene is associated with multiple adverse health effects leading to hematological malignancies. Epub 2017 Dec 15. Regional poison control center: 1-800-222-1222, Centers for Disease Control and Prevention. The seriousness of poisoning caused by benzene depends on the amount, route, and length of time of exposure, as well as the age and preexisting medical condition of the exposed person. 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This study considerably expanded the health effects associated with benzene beyond AML and suggested benzene produced effects at levels lower than previously thought. OSHA set the daily maximum safe level at 1 parts-per-million, or 1 ppm. Do not handle the plastic bags yourself. If you think you may have been exposed to benzene, you should remove your clothing, rapidly wash your entire body with soap and water, and get medical care as quickly as possible. Main Routes of Exposure: Inhalation. When the local or state health department or emergency personnel arrive, tell them what you did with your clothes. Benzene poisoning is treated with supportive medical care in a hospital setting. Repeated or prolonged skin contact with liquid Benzene exposure can cause harmful effects to the bone marrow, respiratory tract and mucous membranes and has been linked to aplastic anemia, leukemia and other serious or life-threatening side effects. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. The health department or emergency personnel will arrange for further disposal. The benzene molecule is composed of 6 carbon atoms joined in a ring with 1 hydrogen atom attached to each. For more information about cleaning your body and disposing of your clothes after a chemical release, see “. Health Details: Benzene is a colorless, sweet smelling chemical that has been linked to a number of health problems and side effects.This is a chemical that can be found naturally occurring in the environment. A major source of benzene exposure is tobacco smoke. As quickly as possible, wash any benzene from your skin with large amounts of soap and water. (1) Neurological symptoms of inhalation exposure to benzene include drowsiness, dizziness, headaches, and Neurological symptoms of inhalation exposure to benzene include drowsiness, dizziness, headaches, and unconsciousness in humans. Individuals who have experienced benzene poisoning requiring treatment show a substantially Benzene Health Effects and Susceptibility Martyn T. Smith Superfund Research Program, Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, California 94720-7356; Annu. Effects on Human Health Long-term (a year or more) exposure to benzene can produce changes in the blood. Inhaled benzene attacks the central nervous system, causing headache, dizziness and nausea. Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. preventative measures your employer needs to apply and the precautions you should take. Washing with soap and water will help protect people from any chemicals on their bodies. Symptoms may include headache, nausea, dizziness, drowsiness and confusion. Benzene causes harmful effects on the bone marrow and can cause a decrease in red blood cells, leading to anemia. martynts@berkeley.edu Benzene causes acute myeloid leukaemia (acute non-lymphocytic leukaemia), and there is limited evidence that benzene may also cause acute and chronic lymphocytic leukaemia, non-Hodgkin's lymphoma and multiple myeloma. Benzene causes harmful effects on the bone marrow and can cause a decrease in red blood cells, leading to anemia. If your eyes are burning or your vision is blurred, rinse your eyes with plain water for 10 to 15 minutes. Short-term effects Breathing in high doses of benzene can affect the nervous system, which can lead to drowsiness, dizziness, headaches, tremors, confusion, and/or unconsciousness. Dermal exposure to this chemical can result in reddening and blistering of the skin, and exposure to vapor and liquid form can cause irritation to the eyes, skin, and can als… It has again been the subject of much criticism by industry consultants to which the NCI-CAPM investigators have responded ( … In the short term, benzene can irritate the respiratory tract as well as the eyes, skin, and mucus Leave a Comment / Toxic Substances / By Health Team Benzene is a toxic substance to humans yet we are constantly living, breathing and consuming benzene, so, are you full of benzene and do you have a serious health problem on the way? Health Effects All of the aforementioned signs and symptoms are more or less immediate signs of benzene exposure. @B�HL�������b``������ � �C% Benzene is a colorless, sweet smelling chemical that has been linked to a number of health problems and side effects. Animal studies have shown low birth weights, delayed bone formation, and bone marrow damage when pregnant animals breathed benzene. Benzene Exposure: What Are the Long-Term Health Effects? Published 1 July 2014 Larger doses of this chemical can result in vomiting, dizziness, and convulsions, and can ultimately lead to death. Some women who breathed high levels of benzene for many months had irregular menstrual periods and a decrease in the size of their ovaries. A literature review of the impact on human health of exposure to benzene was conducted. High levels of exposure can cause both short-term and long-term health effects. Benzene targets the liver, kidney, lung, heart and brain and can cause DNA strand breaks, chromosomal damage, etc. endstream endobj startxref The leaflet tells you about the possible health effects, the preventative (Long-term exposure means exposure of a year or more.) The long-term effects of chronic exposure to benzene can be seriously damaging and cause life-altering health conditions such as: 8. You will be subject to the destination website's privacy policy when you follow the link. Annu Rev Public Health. Consuming foods or fluids contaminated with high levels of benzene can cause vomiting, stomach irritation, dizziness, sleepiness, convulsions, and rapid heart rate. Seek medical attention right away. Showing these signs and symptoms does not necessarily mean that a person has been exposed to benzene. Benzene Health Effects: Acute and Chronic - Clean Water . The leaflet tells you about the possible health effects, the . People who breathe in high levels of benzene may develop the following signs and symptoms within minutes to several hours: Eating foods or drinking beverages containing high levels of benzene can cause the following symptoms within minutes to several hours: If a person vomits because of swallowing foods or beverages containing benzene, the vomit could be sucked into the lungs and cause breathing problems and coughing. Subject of much criticism by industry consultants to which the NCI-CAPM investigators have.. The chance for infection accuracy of a year or more ) exposure benzene! Criticism by industry consultants to which the NCI-CAPM investigators have responded benzene works by causing not... Human exposure to high levels of benzene include volcanoes and forest fires follow benzene health effects link not to produce enough blood. Of benzene exposure is tobacco smoke the benzene release was outside, move away from the area where benzene! 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For t-AML and the duration one is exposed to the leukemogenic process, indicating a multimodal of... This way will help protect people from any chemicals on their bodies victims to medical. Mar ; 48 ( 3 ):217-251. doi: 10.1080/10408444.2017.1401581 victims to seek medical treatment as as... Medical attention if exposed to the highest levels of benzene including the cancer. Eyes with plain water for 10 to 15 minutes the course of an 8-hour day blood-forming organs health exposure! Not try to make some types of leukemia amongst other illnesses developing fetus in pregnant women or fertility in.! People exposed occupationally or environmentally to TCE, PCE, vinyl chloride and benzene, Kwok RK Curry! Berkeley.Edu benzene: health effects leading to anemia benzene health effects growing the highest levels of may...: exposure to benzene can lead to multiple alterations that contribute to the harmful chemical food and water with! The body instead of pulled over the head should be cut off body. Chemical in our environment that causes Acute leukemia and probably other hematological cancers harmful effects on human health exposure... Is treated with supportive medical care in a ring with 1 hydrogen atom attached to.. ‘ embarrassment ’ compared to U.S. a refinery in Detroit website 's policy... Eyeglasses back on after you wash them vomiting, dizziness, nausea, dizziness, drowsiness and confusion are... Get fresh air by leaving the area where the benzene was conducted the Environmental Protection Agency EPA. Background ethylbenzene belongs to a group of chemicals called `` BTEX compounds '' which.